Ontology highlight
ABSTRACT:
SUBMITTER: Caramori ML
PROVIDER: S-EPMC3699823 | biostudies-other | 2013 Jun
REPOSITORIES: biostudies-other
Caramori M Luiza ML Parks Alicia A Mauer Michael M
Journal of the American Society of Nephrology : JASN 20130516 7
Whether early glomerular, tubulointerstitial, vascular, and global glomerulosclerotic lesions can predict progression of diabetic nephropathy is not well defined. Here, we sought to determine whether renal structural parameters predict the development of proteinuria or ESRD after long-term follow-up. We measured several renal structures in kidney biopsies from 94 normoalbuminuric patients with longstanding type 1 diabetes using unbiased morphometric methods. Greater width of the glomerular basem ...[more]