Ontology highlight
ABSTRACT:
SUBMITTER: Shehabi Y
PROVIDER: S-EPMC3706847 | biostudies-other | 2013 Jun
REPOSITORIES: biostudies-other
Shehabi Yahya Y Bellomo Rinaldo R Mehta Sangeeta S Riker Richard R Takala Jukka J
Critical care (London, England) 20130613 3
Despite the universal prescription of sedative drugs in the intensive care unit (ICU), current practice is not guided by high-level evidence. Landmark sedation trials have made significant contributions to our understanding of the problems associated with ICU sedation and have promoted changes to current practice. We identified challenges and limitations of clinical trials which reduced the generalizability and the universal adoption of key interventions. We present an international perspective ...[more]