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The phylogeny of permanent prostate brachytherapy.


ABSTRACT: Permanent prostate brachytherapy has been practiced for more than a century. This review examines the influence of earlier procedures on the modern transperineal ultrasound-directed technique. A literature review was conducted to examine the origin of current clinical practice. The dimensions of the modern brachytherapy seed, the prescription dose, and implant/teletherapy sequencing are vestigial features, which may be suboptimal in the current era of low-energy photon-emitting radionuclides and computerized dose calculations. Although the modern transperineal permanent prostate implant procedure has proven to be safe and effective, it should undergo continuous re-evaluation and evolution to ensure that its potential is maximized.

SUBMITTER: Aronowitz JN 

PROVIDER: S-EPMC3708145 | biostudies-other | 2013 Jun

REPOSITORIES: biostudies-other

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The phylogeny of permanent prostate brachytherapy.

Aronowitz Jesse N JN   Rivard Mark J MJ  

Journal of contemporary brachytherapy 20130628 2


Permanent prostate brachytherapy has been practiced for more than a century. This review examines the influence of earlier procedures on the modern transperineal ultrasound-directed technique. A literature review was conducted to examine the origin of current clinical practice. The dimensions of the modern brachytherapy seed, the prescription dose, and implant/teletherapy sequencing are vestigial features, which may be suboptimal in the current era of low-energy photon-emitting radionuclides and  ...[more]

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