Ontology highlight
ABSTRACT:
SUBMITTER: Kijak GH
PROVIDER: S-EPMC3785804 | biostudies-other | 2013 Oct
REPOSITORIES: biostudies-other
AIDS research and human retroviruses 20130802 10
The advent of next generation sequencing technologies is providing new insight into HIV-1 diversity and evolution, which has created the need for bioinformatics tools that could be applied to the characterization of viral quasispecies. Here we present Nautilus, a bioinformatics package for the analysis of HIV-1 targeted deep sequencing data. The DeepHaplo module determines the nucleotide base frequency and read depth at each position and computes the haplotype frequencies based on the linkage am ...[more]