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Flunarizinium hydrogen maleate.

ABSTRACT: In the cation of the title salt {systematic name: 4-[bis-(4-fluoro-phen-yl)meth-yl]-1-[(2E)-3-phenyl-prop-2-en-1-yl]piperazin-1-ium hydrogen maleate}, C26H27F2N2 (+)·C4H3O4 (-), the protonated piperazine ring is in a chair conformation. The dihedral angle between the 4-fluoro-phenyl rings is 68.2?(2)°. An intra-molecular O-H?O hydrogen bond occurs in the anion. In the crystal, N-H?O, C-H?O and C-H?F inter-actions are observed, which link the ions into [001] chains.

SUBMITTER: Kavitha CN

PROVIDER: S-EPMC3793824 | biostudies-other | 2013

REPOSITORIES: biostudies-other

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Flunarizinium hydrogen maleate.

Kavitha Channappa N CN Jasinski Jerry P JP Matar Somer M SM Yathirajan H S HS Ramesha A R AR

Acta crystallographica. Section E, Structure reports online 20130727 Pt 8

In the cation of the title salt {systematic name: 4-[bis-(4-fluoro-phen-yl)meth-yl]-1-[(2E)-3-phenyl-prop-2-en-1-yl]piperazin-1-ium hydrogen maleate}, C26H27F2N2 (+)·C4H3O4 (-), the protonated piperazine ring is in a chair conformation. The dihedral angle between the 4-fluoro-phenyl rings is 68.2 (2)°. An intra-molecular O-H⋯O hydrogen bond occurs in the anion. In the crystal, N-H⋯O, C-H⋯O and C-H⋯F inter-actions are observed, which link the ions into [001] chains. ...[more]

PMID: 24109411

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