Ontology highlight
ABSTRACT:
SUBMITTER: Tsoy O
PROVIDER: S-EPMC3794579 | biostudies-other | 2013 Oct
REPOSITORIES: biostudies-other
Tsoy Olga O Yurieva Marina M Kucharavy Andrey A O'Reilly Mary M Mushegian Arcady A
Nucleic acids research 20130719 18
Minimal bacterial gene set comprises the genetic elements needed for survival of engineered bacterium on a rich medium. This set is estimated to include 300-350 protein-coding genes. One way of simplifying an organism with such a minimal genome even further is to constrain the amino acid content of its proteins. In this study, comparative genomics approaches and the results of gene knockout experiments were used to extrapolate the minimal gene set of mollicutes, and bioinformatics combined with ...[more]