Ontology highlight
ABSTRACT:
SUBMITTER: Soo RA
PROVIDER: S-EPMC3795429 | biostudies-other | 2012 Jun
REPOSITORIES: biostudies-other
Current drug targets 20120601 6
Effective systemic treatment of pancreatic cancer remains a major challenge, with progress hampered by drug resistance and treatment related toxicities. Currently available cytotoxic agents as monotherapy or in combination have provided only a modest survival benefit for patients with advanced disease. Disappointing phase III results with gemcitabine-based combinations in patients with advanced pancreatic cancer might be related to poor efficacy of systemic therapies in unselected patients. Futu ...[more]