Ontology highlight
ABSTRACT:
SUBMITTER: Coffman VC
PROVIDER: S-EPMC3798249 | biostudies-other | 2013 Oct
REPOSITORIES: biostudies-other
Coffman Valerie C VC Sees Jennifer A JA Kovar David R DR Wu Jian-Qiu JQ
The Journal of cell biology 20131001 1
Both de novo-assembled actin filaments at the division site and existing filaments recruited by directional cortical transport contribute to contractile ring formation during cytokinesis. However, it is unknown which source is more important. Here, we show that fission yeast formin For3 is responsible for node condensation into clumps in the absence of formin Cdc12. For3 localization at the division site depended on the F-BAR protein Cdc15, and for3 deletion was synthetic lethal with mutations t ...[more]