Ontology highlight
ABSTRACT:
SUBMITTER: Baltan S
PROVIDER: S-EPMC3805855 | biostudies-other | 2013 Oct
REPOSITORIES: biostudies-other
Baltan Selva S Morrison Richard S RS Murphy Sean P SP
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 20131001 4
Understanding how epigenetics influences the process and progress of a stroke could yield new targets and therapeutics for use in the clinic. Experimental evidence suggests that inhibitors of zinc-dependent histone deacetylases can protect neurons, axons, and associated glia from the devastating effects of oxygen and glucose deprivation. While the specific enzymes involved have yet to be clearly identified, there are hints from somewhat selective chemical inhibitors and also from the use of spec ...[more]