Plk1: unexpected roles in DNA replication.
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ABSTRACT: FOR20, a conserved centrosomal protein, is essential for Plk1 to localize to the centrosome during the S phase and regulate DNA replication. The absence of either Plk1 or FOR20 can stall the cell cycle by a previously unknown intra-S phase centrosomal checkpoint.
SUBMITTER: Mandal R
PROVIDER: S-EPMC3817549 | biostudies-other | 2013 Nov
REPOSITORIES: biostudies-other
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