Ontology highlight
ABSTRACT:
SUBMITTER: Bharthuar A
PROVIDER: S-EPMC3876598 | biostudies-other | 2012 Jul
REPOSITORIES: biostudies-other
South Asian journal of cancer 20120701 1
An improved understanding of the biology of renal cell carcinoma (RCC) has led to the development of a number of targeted agents, which has resulted in a paradigm shift in the management of metastatic RCC. We review the current therapeutic strategies for metastatic RCC and present a synopsis of the novel agents in use today with a discussion of the phase III trials that demonstrated their clinical benefit. The management of RCC continues to evolve. The introduction of VEGF and mTOR inhibitors ha ...[more]