Ontology highlight
ABSTRACT:
SUBMITTER: Vandenberg LN
PROVIDER: S-EPMC3912007 | biostudies-other | 2013 Nov
REPOSITORIES: biostudies-other
Vandenberg Laura N LN Lemire Joan M JM Levin Michael M
Communicative & integrative biology 20131114 6
For centuries, scientists and physicians have been captivated by the consistent left-right (LR) asymmetry of the heart, viscera, and brain. A recent study implicated tubulin proteins in establishing laterality in several experimental models, including asymmetric chemosensory receptor expression in C. elegans neurons, polarization of HL-60 human neutrophil-like cells in culture, and asymmetric organ placement in Xenopus. The same mutations that randomized asymmetry in these diverse systems also a ...[more]