Ontology highlight
ABSTRACT:
SUBMITTER: Matsubara T
PROVIDER: S-EPMC39210 | biostudies-other | 1996 Jun
REPOSITORIES: biostudies-other
Matsubara T T Beeman R W RW Shike H H Besansky N J NJ Mukabayire O O Higgs S S James A A AA Burns J C JC
Proceedings of the National Academy of Sciences of the United States of America 19960601 12
The lack of efficient mechanisms for stable genetic transformation of medically important insects, such as anopheline mosquitoes, is the single most important impediment to progress in identifying novel control strategies. Currently available techniques for foreign gene expression in insect cells in culture lack the benefit of stable inheritance conferred by integration. To overcome this problem, a new class of pantropic retroviral vectors has been developed in which the amphotropic envelope is ...[more]