Ontology highlight
ABSTRACT:
SUBMITTER: Xu S
PROVIDER: S-EPMC39238 | biostudies-other | 1996 May
REPOSITORIES: biostudies-other
Proceedings of the National Academy of Sciences of the United States of America 19960501 11
The coding sequence of rat MEK kinase 1 (MEKK1) has been determined from multiple, independent cDNA clones. The cDNA is full-length based on the presence of stop codons in all three reading frames of the 5' untranslated region. Probes from the 5' and the 3' coding sequences both hybridize to a 7-kb mRNA. The open reading frame is 4.5 kb and predicts a protein with molecular mass of 161,225 Da, which is twice the size of the previously published MEKK1 sequence and reveals 801 amino acids of novel ...[more]