Ontology highlight
ABSTRACT:
SUBMITTER: Jimenez F
PROVIDER: S-EPMC394416 | biostudies-other | 1995 Jul
REPOSITORIES: biostudies-other
Jiménez F F Martin-Morris L E LE Velasco L L Chu H H Sierra J J Rosen D R DR White K K
The EMBO journal 19950701 14
The development of the central nervous system in Drosophila is initiated by the segregation of neuroblasts, the neural progenitors, from the embryonic neuroectoderm. This process is guided by at least two classes of genes: the achaete-scute complex (AS-C) proneural genes and the neurogenic genes. It has been known for some time that loss-of-function mutations in the AS-C result in neural hypoplasia and the first observed defect is failure of segregation of a fraction of neuroblasts. Loss-of-func ...[more]