Dehydroevodiamine·HCl Improves Stress-Induced Memory Impairments and Depression Like Behavior in Rats.
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ABSTRACT:
SUBMITTER: Kim HJ
PROVIDER: S-EPMC3951824 | biostudies-other | 2014 Feb
REPOSITORIES: biostudies-other
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Dehydroevodiamine·HCl Improves Stress-Induced Memory Impairments and Depression Like Behavior in Rats.
Kim Hee Jin HJ Shin Ki Young KY Chang Keun-A KA Ahn Sangzin S Choi Hee Soon HS Kim Hye-Sun HS Suh Yoo-Hun YH
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 20140213 1
Dehydroevodiamine·HCl (DHED) has been reported to prevent memory impairment and neuronal cell loss in a rat model with cognitive disturbance. We investigated the effect of DHED on memory impairment and behavioral abnormality caused by stress. We demonstrated that DHED can improve stress-induced memory impairments and depression-like behaviors by using open-field test, Y-maze test and forced swimming test. DHED treatment significantly recovered the decreases in the levels of neural cell adhesion ...[more]
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