Ontology highlight
ABSTRACT:
SUBMITTER: Boardman LA
PROVIDER: S-EPMC3972691 | biostudies-other | 2014 Mar
REPOSITORIES: biostudies-other
Boardman Lisa A LA Litzelman Kristin K Seo Songwon S Johnson Ruth A RA Vanderboom Russell J RJ Kimmel Grace W GW Cunningham Julie M JM Gangnon Ronald E RE Engelman Corinne D CD Riegert-Johnson Douglas L DL Potter John J Haile Robert R Buchanan Daniel D Jenkins Mark A MA Rider David N DN Thibodeau Stephen N SN Petersen Gloria M GM Skinner Halcyon G HG
Clinical and translational gastroenterology 20140306
<h4>Objectives</h4>Telomeres are nucleoprotein structures that cap the end of chromosomes and shorten with sequential cell divisions in normal aging. Short telomeres are also implicated in the incidence of many cancers, but the evidence is not conclusive for colorectal cancer (CRC). Therefore, the aim of this study was to assess the association of CRC and telomere length.<h4>Methods</h4>In this case-control study, we measured relative telomere length from peripheral blood leukocytes (PBLs) DNA w ...[more]