Ontology highlight
ABSTRACT:
SUBMITTER: Das S
PROVIDER: S-EPMC3986834 | biostudies-other | 2014 May
REPOSITORIES: biostudies-other
Das Soumita S Sarkar Arup A Ryan Kieran A KA Fox Sarah S Berger Alice H AH Juncadella Ignacio J IJ Bimczok Diane D Smythies Lesley E LE Harris Paul R PR Ravichandran Kodi S KS Crowe Sheila E SE Smith Phillip D PD Ernst Peter B PB
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20140207 5
After Helicobacter pylori infection in humans, gastric epithelial cells (GECs) undergo apoptosis due to stimulation by the bacteria or inflammatory cytokines. In this study, we assessed the expression and function of brain angiogenesis inhibitor 1 (BAI1) in the engulfment of apoptotic GECs using human tissue and cells. After induction of apoptosis by H. pylori or camptothecin, there was a 5-fold increase in the binding of apoptotic GECs to THP-1 cells or peripheral blood monocyte-derived macroph ...[more]