Ontology highlight
ABSTRACT:
SUBMITTER: Rigoli JW
PROVIDER: S-EPMC3993784 | biostudies-other | 2014 Mar
REPOSITORIES: biostudies-other
Rigoli Jared W JW Guzei Ilia A IA Schomaker Jennifer M JM
Organic letters 20140311 6
A highly diastereoselective Ru-catalyzed oxidation/reduction sequence of bicyclic methyleneaziridines provides a facile route to complex 1-amino-2,3-diol motifs. The relative anti stereochemistry between the amine and the vicinal alcohol are proposed to result from 1,3-bischelation in the transition state by the C1 and C3 heteroatoms. ...[more]