Ontology highlight
ABSTRACT:
SUBMITTER: Olsen LC
PROVIDER: S-EPMC401392 | biostudies-other | 1989 Oct
REPOSITORIES: biostudies-other
Olsen L C LC Aasland R R Wittwer C U CU Krokan H E HE Helland D E DE
The EMBO journal 19891001 10
Uracil-DNA glycosylase is the DNA repair enzyme responsible for the removal of uracil from DNA, and it is present in all organisms investigated. Here we report on the cloning and sequencing of a cDNA encoding the human uracil-DNA glycosylase. The sequences of uracil-DNA glycosylases from yeast, Escherichia coli, herpes simplex virus type 1 and 2, and homologous genes from varicella-zoster and Epstein-Barr viruses are known. It is shown in this report that the predicted amino acid sequence of the ...[more]