Creating the feedback loop: closed-loop neurostimulation.
Ontology highlight
ABSTRACT:
SUBMITTER: Hebb AO
PROVIDER: S-EPMC4058859 | biostudies-other | 2014 Jan
REPOSITORIES: biostudies-other
Publications
Creating the feedback loop: closed-loop neurostimulation.
Hebb Adam O AO Zhang Jun Jason JJ Mahoor Mohammad H MH Tsiokos Christos C Matlack Charles C Chizeck Howard Jay HJ Pouratian Nader N
Neurosurgery clinics of North America 20131023 1
Current DBS therapy delivers a train of electrical pulses at set stimulation parameters. This open-loop design is effective for movement disorders, but therapy may be further optimized by a closed loop design. The technology to record biosignals has outpaced our understanding of their relationship to the clinical state of the whole person. Neuronal oscillations may represent or facilitate the cooperative functioning of brain ensembles, and may provide critical information to customize neuromodul ...[more]
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