Ontology highlight
ABSTRACT:
SUBMITTER: Cheung GY
PROVIDER: S-EPMC4087065 | biostudies-other | 2014 Jul
REPOSITORIES: biostudies-other
Cheung Gordon Y C GY Villaruz Amer E AE Joo Hwang-Soo HS Duong Anthony C AC Yeh Anthony J AJ Nguyen Thuan H TH Sturdevant Daniel E DE Queck S Y SY Otto M M
International journal of medical microbiology : IJMM 20140428 5-6
Several methicillin resistance (SCCmec) clusters characteristic of hospital-associated methicillin-resistant Staphylococcus aureus (MRSA) strains harbor the psm-mec locus. In addition to encoding the cytolysin, phenol-soluble modulin (PSM)-mec, this locus has been attributed gene regulatory functions. Here we employed genome-wide transcriptional profiling to define the regulatory function of the psm-mec locus. The immune evasion factor protein A emerged as the primary conserved and strongly regu ...[more]