Ontology highlight
ABSTRACT:
SUBMITTER: Feillet C
PROVIDER: S-EPMC4103330 | biostudies-other | 2014 Jul
REPOSITORIES: biostudies-other
Feillet Céline C Krusche Peter P Tamanini Filippo F Janssens Roel C RC Downey Mike J MJ Martin Patrick P Teboul Michèle M Saito Shoko S Lévi Francis A FA Bretschneider Till T van der Horst Gijsbertus T J GT Delaunay Franck F Rand David A DA
Proceedings of the National Academy of Sciences of the United States of America 20140623 27
Daily synchronous rhythms of cell division at the tissue or organism level are observed in many species and suggest that the circadian clock and cell cycle oscillators are coupled. For mammals, despite known mechanistic interactions, the effect of such coupling on clock and cell cycle progression, and hence its biological relevance, is not understood. In particular, we do not know how the temporal organization of cell division at the single-cell level produces this daily rhythm at the tissue lev ...[more]