Genes Downregulated in Endometriosis Are Located Near the Known Imprinting Genes.
Ontology highlight
ABSTRACT:
SUBMITTER: Kobayashi H
PROVIDER: S-EPMC4126219 | biostudies-other | 2014 Aug
REPOSITORIES: biostudies-other
Publications
Genes Downregulated in Endometriosis Are Located Near the Known Imprinting Genes.
Kobayashi Hiroshi H Higashiura Yumi Y Koike Natsuki N Akasaka Juria J Uekuri Chiharu C Iwai Kana K Niiro Emiko E Morioka Sachiko S Yamada Yuki Y
Reproductive sciences (Thousand Oaks, Calif.) 20140310 8
There is now accumulating evidence that endometriosis is a disease associated with an epigenetic disorder. Genomic imprinting is an epigenetic phenomenon known to regulate DNA methylation of either maternal or paternal alleles. We hypothesize that hypermethylated endometriosis-associated genes may be enriched at imprinted gene loci. We sought to determine whether downregulated genes associated with endometriosis susceptibility are associated with chromosomal location of the known paternally and ...[more]
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