Ontology highlight
ABSTRACT:
SUBMITTER: Swygert SG
PROVIDER: S-EPMC4151189 | biostudies-other | 2014 Aug
REPOSITORIES: biostudies-other
Nature communications 20140828
Heterochromatin is a repressive chromatin compartment essential for maintaining genomic integrity. A hallmark of heterochromatin is the presence of specialized nonhistone proteins that alter chromatin structure to inhibit transcription and recombination. It is generally assumed that heterochromatin is highly condensed. However, surprisingly little is known about the structure of heterochromatin or its dynamics in solution. In budding yeast, formation of heterochromatin at telomeres and the homot ...[more]