Ontology highlight
ABSTRACT:
SUBMITTER: Zaro BW
PROVIDER: S-EPMC4168799 | biostudies-other | 2014 Sep
REPOSITORIES: biostudies-other
ACS chemical biology 20140729 9
Metabolic chemical reporters have been largely used to study posttranslational modifications. Generally, it was assumed that these reporters entered one biosynthetic pathway, resulting in labeling of one type of modification. However, because they are metabolized by cells before their addition onto proteins, metabolic chemical reporters potentially provide a unique opportunity to read-out on both modifications of interest and cellular metabolism. We report here the development of a metabolic che ...[more]