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Pharmacotherapy for uveitis: current management and emerging therapy.


ABSTRACT: Uveitis, a group of conditions characterized by intraocular inflammation, is a major cause of sight loss in the working population. Most uveitis seen in Western countries is noninfectious and appears to be autoimmune or autoinflammatory in nature, requiring treatment with immunosuppressive and/or anti-inflammatory drugs. In this educational review, we outline the ideal characteristics of drugs for uveitis and review the data to support the use of current and emerging therapies in this context. It is crucial that we continue to develop new therapies for use in uveitis that aim to suppress disease activity, prevent accumulation of damage, and preserve visual function for patients with the minimum possible side effects.

SUBMITTER: Barry RJ 

PROVIDER: S-EPMC4181632 | biostudies-other | 2014

REPOSITORIES: biostudies-other

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Pharmacotherapy for uveitis: current management and emerging therapy.

Barry Robert J RJ   Nguyen Quan Dong QD   Lee Richard W RW   Murray Philip I PI   Denniston Alastair K AK  

Clinical ophthalmology (Auckland, N.Z.) 20140922


Uveitis, a group of conditions characterized by intraocular inflammation, is a major cause of sight loss in the working population. Most uveitis seen in Western countries is noninfectious and appears to be autoimmune or autoinflammatory in nature, requiring treatment with immunosuppressive and/or anti-inflammatory drugs. In this educational review, we outline the ideal characteristics of drugs for uveitis and review the data to support the use of current and emerging therapies in this context. I  ...[more]

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