Evidence for cross-pathway regulation of metabolic gene expression in plants.
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ABSTRACT:
SUBMITTER: Guyer D
PROVIDER: S-EPMC41834 | biostudies-other | 1995 May
REPOSITORIES: biostudies-other
Publications
Evidence for cross-pathway regulation of metabolic gene expression in plants.
Proceedings of the National Academy of Sciences of the United States of America 19950501 11
In Arabidopsis thaliana, blocking histidine biosynthesis with a specific inhibitor of imidazoleglycerol-phosphate dehydratase caused increased expression of eight genes involved in the biosynthesis of aromatic amino acids, histidine, lysine, and purines. A decrease in expression of glutamine synthetase was also observed. Addition of histidine eliminated the gene-regulating effects of the inhibitor, demonstrating that the changes in gene expression resulted from histidine-pathway blockage. These ...[more]
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