Ontology highlight
ABSTRACT:
SUBMITTER: Lanni EJ
PROVIDER: S-EPMC4221875 | biostudies-other | 2014 Nov
REPOSITORIES: biostudies-other
Lanni Eric J EJ Masyuko Rachel N RN Driscoll Callan M CM Dunham Sage J B SJ Shrout Joshua D JD Bohn Paul W PW Sweedler Jonathan V JV
Analytical chemistry 20141013 21
Secondary ion mass spectrometry (SIMS) and confocal Raman microscopy (CRM) are combined to analyze the chemical composition of cultured Pseudomonas aeruginosa biofilms, providing complementary chemical information for multiple analytes within the sample. Precise spatial correlation between SIMS and CRM images is achieved by applying a chemical microdroplet array to the sample surface which is used to navigate the sample, relocate regions of interest, and align image data. CRM is then employed to ...[more]