Ontology highlight
ABSTRACT:
SUBMITTER: Garnett-Benson C
PROVIDER: S-EPMC4258617 | biostudies-other | 2015 Jan
REPOSITORIES: biostudies-other
Seminars in radiation oncology 20150101 1
Radiation therapy (RT) is widely used with curative or palliative intent in the clinical management of multiple cancers. Although mainly aimed at direct tumor cell killing, mounting evidence suggests that radiation can alter the tumor to become an immunostimulatory milieu. Data suggest that the immunogenic effects of radiation can be exploited to promote synergistic antitumor effects in combination with immunotherapeutic agents. We review concepts associated with the immunogenic consequences of ...[more]