Ontology highlight
ABSTRACT:
SUBMITTER: Salavati B
PROVIDER: S-EPMC4266301 | biostudies-other | 2015 Jan
REPOSITORIES: biostudies-other
Salavati Bahar B Rajji Tarek K TK Price Rae R Sun Yinming Y Graff-Guerrero Ariel A Daskalakis Zafiris J ZJ
Schizophrenia bulletin 20140922 1
Cognitive deficits are commonly observed in patients with schizophrenia. Converging lines of evidence suggest that these deficits are associated with impaired long-term potentiation (LTP). In our systematic review, this hypothesis is evaluated using neuroimaging literature focused on proton magnetic resonance spectroscopy, positron emission tomography, and single-photon emission computed tomography. The review provides evidence for abnormal dopaminergic, GABAergic, and glutamatergic neurotransmi ...[more]