Ontology highlight
ABSTRACT:
SUBMITTER: Duluc D
PROVIDER: S-EPMC4268898 | biostudies-other | 2014
REPOSITORIES: biostudies-other
Duluc Dorothée D Banchereau Romain R Gannevat Julien J Thompson-Snipes Luann L Blanck Jean-Philippe JP Zurawski Sandra S Zurawski Gerard G Hong Seunghee S Rossello-Urgell Jose J Pascual Virginia V Baldwin Nicole N Stecher Jack J Carley Michael M Boreham Muriel M Oh SangKon S
Genome medicine 20141125 11
<h4>Background</h4>Dendritic cells localize throughout the body, where they can sense and capture invading pathogens to induce protective immunity. Hence, harnessing the biology of tissue-resident dendritic cells is fundamental for the rational design of vaccines against pathogens.<h4>Methods</h4>Herein, we characterized the transcriptomes of four antigen-presenting cell subsets from the human vagina (Langerhans cells, CD14(-) and CD14(+) dendritic cells, macrophages) by microarray, at both the ...[more]