B cells for cancer immunotherapy.
Ontology highlight
ABSTRACT: We have engineered a novel fusion cytokine named GIFT4 derived from GM-CSF and IL-4, and displaying robust gain-of-function immunostimulatory effects on B cells. GIFT4-programmed B cells have a unique identity and potent capacity to elicit a tumoricidal - cell response, thus comprising a novel B cell-based cancer immunotherapeutic approach.
SUBMITTER: Deng J
PROVIDER: S-EPMC4292730 | biostudies-other | 2014 Nov
REPOSITORIES: biostudies-other
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