Is the scavenger receptor MARCO a new immune checkpoint?
Ontology highlight
ABSTRACT: Whereas macrophages use the scavenger receptor MARCO primarily in antimicrobial immunity by interacting with both exogenous and endogenous environments, in dendritic cells (DCs) MARCO is believed to pleiotropically link innate to adaptive immunity. MARCO exerts a significant modulatory effect on TLR-induced DC activation, thus offering novel avenues in cancer immunotherapy.
SUBMITTER: Arredouani MS
PROVIDER: S-EPMC4292731 | biostudies-other | 2014 Nov
REPOSITORIES: biostudies-other
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