Ontology highlight
ABSTRACT:
SUBMITTER: Marras AE
PROVIDER: S-EPMC4311804 | biostudies-other | 2015 Jan
REPOSITORIES: biostudies-other
Marras Alexander E AE Zhou Lifeng L Su Hai-Jun HJ Castro Carlos E CE
Proceedings of the National Academy of Sciences of the United States of America 20150105 3
DNA origami enables the precise fabrication of nanoscale geometries. We demonstrate an approach to engineer complex and reversible motion of nanoscale DNA origami machine elements. We first design, fabricate, and characterize the mechanical behavior of flexible DNA origami rotational and linear joints that integrate stiff double-stranded DNA components and flexible single-stranded DNA components to constrain motion along a single degree of freedom and demonstrate the ability to tune the flexibil ...[more]