Ontology highlight
ABSTRACT:
SUBMITTER: Mekada K
PROVIDER: S-EPMC4329520 | biostudies-other | 2015
REPOSITORIES: biostudies-other
Mekada Kazuyuki K Hirose Mayu M Murakami Ayumi A Yoshiki Atsushi A
Experimental animals 20141023 1
C57BL/6N inbred mice are used as the genetic background for producing knockout mice in large-scale projects worldwide; however, the genetic divergence among C57BL/6N-derived substrains has not been verified. Here, we identified novel single nucleotide polymorphisms (SNPs) specific to the C57BL/6NJ strain and selected useful SNPs for the genetic monitoring of C57BL/6N-derived substrains. Informative SNPs were selected from the public SNP database at the Wellcome Trust Sanger Institute by comparin ...[more]