A family of cellular proteins related to snake venom disintegrins.
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ABSTRACT:
SUBMITTER: Weskamp G
PROVIDER: S-EPMC43447 | biostudies-other | 1994 Mar
REPOSITORIES: biostudies-other
Publications
A family of cellular proteins related to snake venom disintegrins.
Proceedings of the National Academy of Sciences of the United States of America 19940301 7
Disintegrins are short soluble integrin ligands that were initially identified in snake venom. A previously recognized cellular protein with a disintegrin domain was the guinea pig sperm protein PH-30, a protein implicated in sperm-egg membrane binding and fusion. Here we present peptide sequences that are characteristic for several cellular disintegrin-domain proteins. These peptide sequences were deduced from cDNA sequence tags that were generated by polymerase chain reaction from various mous ...[more]
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