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Advanced disease at enrollment in HIV care in four sub-Saharan African countries: change from 2006 to 2011 and multilevel predictors in 2011.


ABSTRACT: To examine changes between 2006 and 2011 in the proportion of HIV-positive patients newly enrolled in HIV care with advanced disease and the median CD4 cell count at enrollment; and identify patient, facility, and contextual-level factors associated with late enrollment in care in 2011.Cross-sectional over time.For time-trends analyses, routinely collected patient-level data (307?110 adults newly enrolled in 138 HIV clinical care facilities) in Kenya, Mozambique, Rwanda and Tanzania; and for analyses of correlates, patient-level data (46?201 in 195 facilities), and facility and population-level survey data were used. Late enrollment was defined as CD4 cell count 350?cells/?l or less and/or WHO clinical stage 3/4.Late enrollment declined from 69.9 to 57.2% (P?

SUBMITTER: Hoffman S 

PROVIDER: S-EPMC4361092 | biostudies-other | 2014 Oct

REPOSITORIES: biostudies-other

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Advanced disease at enrollment in HIV care in four sub-Saharan African countries: change from 2006 to 2011 and multilevel predictors in 2011.

Hoffman Susie S   Wu Yingfeng Y   Lahuerta Maria M   Kulkarni Sarah Gorrell SG   Nuwagaba-Biribonwoha Harriet H   Sadr Wafaa El WE   Remien Robert H RH   Mugisha Veronicah V   Hawken Mark M   Chuva Ema E   Nash Denis D   Elul Batya B  

AIDS (London, England) 20141001 16


<h4>Objectives</h4>To examine changes between 2006 and 2011 in the proportion of HIV-positive patients newly enrolled in HIV care with advanced disease and the median CD4 cell count at enrollment; and identify patient, facility, and contextual-level factors associated with late enrollment in care in 2011.<h4>Design</h4>Cross-sectional over time.<h4>Methods</h4>For time-trends analyses, routinely collected patient-level data (307 110 adults newly enrolled in 138 HIV clinical care facilities) in K  ...[more]

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