Ontology highlight
ABSTRACT:
SUBMITTER: Brighenti M
PROVIDER: S-EPMC4402600 | biostudies-other | 2015 Apr
REPOSITORIES: biostudies-other
MicroRNAs (miRNAs) are a class of small non-protein coding RNAs that modulate important cellular functions via their post-transcriptional regulation of messenger RNAs (mRNAs). Recent evidences from multiple tumor types and model systems implicate miRNA dysregulation as a common mechanism of tumorigenesis, cancer progression and resistance to therapy. Several miRNAs are dysregulated in cancers and a single miRNA can have multiple targets involved in different oncogenic pathways. MET, the tyrosine ...[more]