Ontology highlight
ABSTRACT:
SUBMITTER: Luo W
PROVIDER: S-EPMC3667122 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Luo Wenting W Huang Bo B Li Zixuan Z Li Haiying H Sun Limei L Zhang Qingfu Q Qiu Xueshan X Wang Enhua E
PloS one 20130529 5
MicroRNA-449a is expressed at a low level in several tumors and cancer cell lines, and induces G1 arrest, apoptosis, and senescence. To identify the function of miR-449a in non-small cell lung cancer (NSCLC), we discussed the potential relevance of miR-449a to clinicopathological characteristics and prognosis in NSCLC. We also investigated the impact of miR-449a on migration and invasion in NSCLC cells. The expression of miR-449a in NSCLC tissues and cell lines was detected using RT-qPCR. In vit ...[more]