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Author's view: radiation and immunotherapy as systemic therapy for solid tumors.


ABSTRACT: The ability of tumors to evade detection by the immune system via inducing immunosuppression prompted the therapeutic development of immune checkpoint inhibitors. In our recent review, we discussed findings from preclinical and clinical investigations of these agents utilized in combination with radiation inducing abscopal (systemic) antitumor effects.

SUBMITTER: Seyedin SN 

PROVIDER: S-EPMC4404906 | biostudies-other | 2015 Jan

REPOSITORIES: biostudies-other

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