Ontology highlight
ABSTRACT:
SUBMITTER: Li X
PROVIDER: S-EPMC4439250 | biostudies-other | 2011 Apr
REPOSITORIES: biostudies-other
Li Xingnan X Franke Adrian A AA
Analytical chemistry 20110323 8
We report a new method for fast and sensitive analyses of biologically relevant fatty acids (FAs) in red blood cells (RBC) by liquid chromatography mass spectrometry (LC-MS). A new chemical derivatization approach was developed forming picolylamides from FAs in a quantitative reaction. Fourteen derivatized FA standards, including saturated and unsaturated FAs from C14 to C22, were efficiently separated within 15 min. In addition, the use of a recently introduced benchtop orbitrap mass spectromet ...[more]