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Data on force-dependent structural changes of chromatin fibers measured with magnetic tweezers.


ABSTRACT: The compaction of chromatin fibers regulates the accessibility of embedded DNA, highly associated with transcriptional activities [1]. Single molecule force spectroscopy has revealed the great details of the structural changes of chromatin fibers in the presence of external exerted force [2-7]. However, most of the studies focus on a specific force regime [2,3,8,9]. The data here show force-extension (FE) traces of chromatin fibers as measured with magnetic tweezers, covering the force regime from 0 pN to 27 pN. Those traces provide information for further studies at varied force regimes.

SUBMITTER: Chien FT 

PROVIDER: S-EPMC4459773 | biostudies-other | 2014 Dec

REPOSITORIES: biostudies-other

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Data on force-dependent structural changes of chromatin fibers measured with magnetic tweezers.

Chien Fan-Tso FT  

Data in brief 20140806


The compaction of chromatin fibers regulates the accessibility of embedded DNA, highly associated with transcriptional activities [1]. Single molecule force spectroscopy has revealed the great details of the structural changes of chromatin fibers in the presence of external exerted force [2-7]. However, most of the studies focus on a specific force regime [2,3,8,9]. The data here show force-extension (FE) traces of chromatin fibers as measured with magnetic tweezers, covering the force regime fr  ...[more]

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