Ontology highlight
ABSTRACT:
SUBMITTER: te Velthuis AJ
PROVIDER: S-EPMC2920648 | biostudies-literature | 2010 Aug
REPOSITORIES: biostudies-literature
te Velthuis Aartjan J W AJ Kerssemakers Jacob W J JW Lipfert Jan J Dekker Nynke H NH
Biophysical journal 20100801 4
Single-molecule techniques are powerful tools that can be used to study the kinetics and mechanics of a variety of enzymes and their complexes. Force spectroscopy, for example, can be used to control the force applied to a single molecule and thereby facilitate the investigation of real-time nucleic acid-protein interactions. In magnetic tweezers, which offer straightforward control and compatibility with fluorescence measurements or parallel tracking modes, force-measurement typically relies on ...[more]