Ontology highlight
ABSTRACT:
SUBMITTER: Strale PO
PROVIDER: S-EPMC4508897 | biostudies-other | 2015 Jul
REPOSITORIES: biostudies-other
Strale Pierre-Olivier PO Duchesne Laurence L Peyret Grégoire G Montel Lorraine L Nguyen Thao T Png Evelyn E Tampé Robert R Troyanovsky Sergey S Hénon Sylvie S Ladoux Benoit B Mège René-Marc RM
The Journal of cell biology 20150701 2
Oligomerization of cadherins could provide the stability to ensure tissue cohesion. Cadherins mediate cell-cell adhesion by forming trans-interactions. They form cis-interactions whose role could be essential to stabilize intercellular junctions by shifting cadherin clusters from a fluid to an ordered phase. However, no evidence has been provided so far for cadherin oligomerization in cellulo and for its impact on cell-cell contact stability. Visualizing single cadherins within cell membrane at ...[more]