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Why Have So Many Intravascular Glucose Monitoring Devices Failed?

ABSTRACT: Secondary to the inherent limitations of both point-of-care and central laboratory glucose technologies, continuous glucose measurement has recently enjoyed a high level of investment. Because of the perceived advantages by some of measuring in the intravascular space compared to the subcutaneous tissue, a number of technologies have been developed. In this review, we evaluate nine systems that have shown promise, although only one of these has been cleared for sale in the United States. The detection methodology, regulatory status, technical issues, and company circumstance surrounding each technology are examined.

SUBMITTER: Smith JL

PROVIDER: S-EPMC4525646 | biostudies-other | 2015 Jul

REPOSITORIES: biostudies-other

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Why Have So Many Intravascular Glucose Monitoring Devices Failed?

Smith John L JL Rice Mark J MJ

Journal of diabetes science and technology 20150701 4

Secondary to the inherent limitations of both point-of-care and central laboratory glucose technologies, continuous glucose measurement has recently enjoyed a high level of investment. Because of the perceived advantages by some of measuring in the intravascular space compared to the subcutaneous tissue, a number of technologies have been developed. In this review, we evaluate nine systems that have shown promise, although only one of these has been cleared for sale in the United States. The det ...[more]

PMID: 26129733

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