Therapeutic potential of interleukin-27 against cancers in preclinical mouse models.
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ABSTRACT: Since we first reported the antitumor efficacy of IL-27 in 2004, accumulating evidence obtained by several groups using a variety of preclinical mouse models indicates that IL-27 possesses potent antitumor activity against various types of tumors through multiple mechanisms depending on the characteristics of individual tumors without apparent adverse effects.
SUBMITTER: Mizoguchi I
PROVIDER: S-EPMC4589049 | biostudies-other | 2015 Oct
REPOSITORIES: biostudies-other
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