Ontology highlight
ABSTRACT:
SUBMITTER: Alfano LN
PROVIDER: S-EPMC4590682 | biostudies-other | 2015
REPOSITORIES: biostudies-other
Therapeutics and clinical risk management 20150925
Sporadic inclusion body myositis is the most common inflammatory muscle disorder preferentially affecting males over the age of 40 years. Progressive muscle weakness of the finger flexors and quadriceps muscles results in loss of independence with activities of daily living and eventual wheelchair dependence. Initial signs of disease are often overlooked and can lead to mis- or delayed diagnosis. The underlying cause of disease is unknown, and disease progression appears refractory to available ...[more]