Diurnal rhythms in the human urine metabolome during sleep and total sleep deprivation.
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ABSTRACT:
SUBMITTER: Giskeodegard GF
PROVIDER: S-EPMC4598809 | biostudies-other | 2015
REPOSITORIES: biostudies-other
Publications
Diurnal rhythms in the human urine metabolome during sleep and total sleep deprivation.
Giskeødegård Guro F GF Davies Sarah K SK Revell Victoria L VL Keun Hector H Skene Debra J DJ
Scientific reports 20151009
Understanding how metabolite levels change over the 24 hour day is of crucial importance for clinical and epidemiological studies. Additionally, the association between sleep deprivation and metabolic disorders such as diabetes and obesity requires investigation into the links between sleep and metabolism. Here, we characterise time-of-day variation and the effects of sleep deprivation on urinary metabolite profiles. Healthy male participants (n = 15) completed an in-laboratory study comprising ...[more]
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