Ontology highlight
ABSTRACT:
SUBMITTER: Hoffman RM
PROVIDER: S-EPMC4621256 | biostudies-other | 2015 Nov
REPOSITORIES: biostudies-other
Hoffman Risa M RM Jaycocks Amber A Vardavas Raffaele R Wagner Glenn G Lake Jordan E JE Mindry Deborah D Currier Judith S JS Landovitz Raphael J RJ
The Journal of infectious diseases 20150619 10
<h4>Background</h4>Data on effectiveness of preexposure prophylaxis (PrEP) for human immunodeficiency virus (HIV)-uninfected women attempting conception with HIV-infected male partners are limited to observational studies.<h4>Methods</h4>To explore the benefits of PrEP for conception, we developed a model to estimate the average annual probability of a woman remaining HIV-uninfected and having a child ("successful" outcome) via condomless sex with an HIV-infected male. The outcome likelihood is ...[more]